Dr. Tan and Partners is one of the few approved Anonymous HIV Testing Centres in Singapore. A detailed write up on our service is available here.

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HIV 4th Generation Test Singapore

The HIV 4th Generation Test is one of the most accurate and fastest way to determine is a person has been infected with HIV or not.

The HIV 4th Generation Test is also called the Combo test or the Duo test.

It tests for both the HIV antibodies as well as the antigens in the blood. It can be done as a rapid test i.e. you can get the results in 20 minutes.

Antibodies are produced by the body when it is infected with the HIV virus. There are many different types of antibodies. The one that is produced the earliest is called the IgM antibody. This can be produced as early as 20 days post exposure. 3rd and 4th Generation HIV tests can detect the IgM antibody.

Antigens are bits of the HIV virus shell that can be found in the blood as early as 14 days post exposure. The 4th Generation test can detect the presence of this antigen.

If the test detects either the presence of HIV antibodies or antigens, it means the patient is most likely infected with HIV. This has to be confirmed with another ELISA test. We always do at least 2 tests before diagnosing a person as HIV +ve.

Officially it is conclusive at 28 days post exposure. However, from current scientific data, we know that when the test is done at 20 days post exposure, it is already as good as 100% accurate. Personally I have tested patients +ve for HIV at only 14 days post exposure with this test.

The US CDC recommends the HIV 4th Generation test for all HIV screening. This is because it is more accurate, has a shorter window period and can pick up rare cases of sero-negative infections (see below).

The HIV 4th Generation test can detect HIV infections in very rare cases of people who are infected with HIV but never produce any anti-bodies. These are called sero-negative infections and happen in about 1 in 1 million people.

At our clinics the HIV 4th Generation test costs $150 (before GST).

You can walk in our clinics at Robertson Walk, Bencoolen Street, Novena Medical Center or Scotts Road anytime during our opening hours for this test. It only requires a finger-prick of blood and 20 minutes to get results.

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Find out more about Anonymous HIV testing at our clinics.

Can’t wait for 3 months to find out? Find out more about Anonymous Rapid HIV Combo test at our clinics.

If you had a high risk exposure to HIV within the past 72 hours, you can take medicines to reduce your risk of actually contracting HIV. Find out more on HIV PEP Treatment.

 

Related Topics:

Anonymous HIV testing at our Clinics

HIV – Understanding the Window Period

Cost of HIV/STD tests at our Clinics

Condom Broke

Getting HIV from Oral Sex

More on HIV symptoms

How long can HIV live outside the body?


 

 

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Need more advice?

Come down to Our Clinics for a discussion with Our Doctors, or call our clinics for more information:

1.) Robertson Walk (Anonymous HIV Clinic)  (+65 6238 7810)

2.) Bencoolen Street (+65 6884 4119)

3.) Novena Medical Centre (+65 6397 2095)

4.) Scotts Medical Centre (+65 6694 2348)

5.) Somerset – Orchard Building (+65 6262 0762)

6.) Katong – East Coast Road (+65 6635 2551)

 

Where to find us – here

Selected clinics are open on Saturday and Sunday.

 

Email: doctor@drtanandpartners.com

 

All Our Doctors are Fully Certified and Trained to conduct specialised HIV Testing.

 

For lady patients who prefer female doctors, we have professional certified female Doctors to attend to your medical needs.

About Dr. Tan
Dr. Tan graduated from the National University of Singapore in 2001. His residency was in the two largest public hospitals in Singapore; Tan Tock Seng Hospital and Singapore General Hospital.

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1,073 Comments

  1. Vetrivelavan

    I went to erotic massage parlor.
    (1.)At one point of time i was Naked and the massage girl was wearing her underwear.
    She sat on top of my penis and lied it on me; in to and fro motion she humped me for 1 min by wearing her underwear.

    Is there any possibility for hiv over here. ?

    Is there any chance my penis would have went inside her vagina even she was wearing her underwear. ?

    The girl was bit cautious that when my precum touched her belly she told me to wear underwear.

    (2.) At the end I finished by rubbing my penis inbetween her Breast.

    Considering above 1 & 2 scenario there is risk for hiv ?

    • I would consider the risk of HIV close to zero from this exposure. If you are still concerned, please see a doctor for a proper consult and evaluation.

      • Vetrivelavan

        Dr,
        Close to zero means there is Risk ?
        So much worried dr.

        • Close to zero means I can’t say there is absolutely zero risk, given that you yourself cannot tell me if there was any penetration. But it sounds very negligible and not something I would worry about. Like I said, if you are still concerned, see a doctor and discuss your situation in person.

  2. Sohal khan

    Dear doctor
    I have protected sex with a girl only 20 second. Then after 50 hours I took pep medicine for 3 days because of fear(only 3 pills one pill Per day). Then after 14 day I took rna par viral load test which came negative.after 26 days I took another test 4th generation HIV 1&2 combo which came negative. After that 43 days I took another 4th generation HIV 1&2 combo test which came negative. After 50 days I took two test one 4th generation HIV 1&2 combo test and another HIV tridot card test both tests came negative. Plz doctor tell about my tests are conclusive or not. Do you think I need for further? testing

    • Dr. Julian Ng

      Hi,

      Your tests are conclusive. Move on.

      • Sohal khan

        Thanks doctor Julian Ng

      • i gave unprotected oral sex to a man with unknown hiv status and i recalled that i have a healing sore when he ejaculated in my mouth. At around the 41st day i did the alere rapid hiv test and it was negative. Do you think it is conclusive or would it become positive after i take another test at the 3 month mark?

        • Dr. Julian Ng

          Hi,

          Oral sex is considered low risk for HIV transmission. I would consider your test to be conclusive if you have tested with a 4th generation HIV test in the time frame you reported.

  3. I test hiv 37 day.4 genaration.hiv Ab/Ag (cmia) : non reactive, after 3 months the results changed positive or no doctor?

  4. Abraham

    Dr ,
    Can a male get high of a woman rubbed her vagina on his butt for several minutes? Is there any chance her blood or vaginal secretions can make it all the way down to my rectal fluids ? Should I just forget about this incident or do I require testing ? Has there ever been a reported case of transmission this way?

    • Get high? If you mean can they get HIV from that form of exposure, I would say realistically there is zero risk.

  5. hi doctor..
    I test hiv 37 day.4 genaration.hiv Ab/Ag (cmia) : non reactive. my hiv test conclusive or test next 90 day?.

    • Dr. Julian Ng

      Hi,

      If you have tested at 37 days post-exposure with a 4th generation HIV test, then it is generally considered as conclusive.

      • I test hiv 37 day.4 genaration.hiv Ab/Ag (cmia) : non reactive, after 3 months the results changed positive or no doctor?

        • Dr. Julian Ng

          Hi,

          As mentioned, your results are conclusive but if you are still concerned, you can consider retesting after 3 months.

  6. Newonehere

    Hi, Doctor!

    I was the receiver of unprotected vaginal sex twice on the same night. I took a CMIA 4th gen test 18 days after, result was non-reactive. I took another another 4th gen CMIA test 27 days and 10 hours after, result was again non-reactive. Are these results conclusive? I started getting symptoms (scratchy throat, post-nasal drip, pinched pain behind the ear, stabbing muscle pains all over the body, ice pick headaches) after the second test so now I’m anxious. How conclusive are my test results?

    • Dr. Julian Ng

      Hi,

      The 4th generation HIV test is only conclusive after 28 days post-exposure. My suggestion is for you to repeat after 28 days.

      • Newonehere

        I took the CMIA test 27 days and 10 hours after. Will 1 day make a big difference? I’m so worried.

  7. Worry Man

    Hi Doc,
    I have done Alere HIV Ag/Ab Combo test after 33 days post exposure.The result is negative. Can I consider the result is conclusive?
    Thank you.

  8. Carlo

    I have a protected sex with sex worker. I test negative on 4th gen and 3rd gen rapid test at 26 days after sex exposure. Would you consider it conclusive? Also negative result on my gram stain analysis for gonorhea. Hope you answer my question.

    • Dr. Julian Ng

      Hi,

      The recommendation is that you will need to be retested 28 days after exposure with a 4th Generation HIV test. As for the gram stain results, it is not the most sensitive test to use. My suggestion would be to screen with PCR instead.

      • Carlo

        Is it a good assurance or good news having non reactive result in 4th gen hiv test at 26 days after exposure

  9. Concern

    Hello Dr,

    I have something to ask you regarding HIV test. I did my hiv test twice after 1 year of exposure, first i did is antibody rapid test and it came out negative. But the dr did the test within 5-7 minutes. So i did 4th gen combo test and also came out negative. Is these tests are conclusive?

    • Dr. Julian Ng

      Hi,

      I would consider your results as conclusive if the 4th Generation test was done 1 yr post-exposure.

  10. Hello dr.
    UnProtected vaginal sex with the unknown girl status.18 days post exposure ive take HIV RNA qulitative assay result was “not detected, 41 days after exposure 3rd gen antibodies result was “negative” 48 days after esposure 4th generation duo test came back “non reactive” is all my result already conclusive???.

    • Dr. Julian Ng

      Hi,

      I would consider you results as conclusive.

  11. Akshay kumar

    Good morning doctor
    I have protected sex with a hiv positive girl.i wore condom beginning to last. No kiss no oral just vaginal sex for 20 second. After that I took pep only 3 days just 3 pills one pill per day. After 14 days explosure I took rna pcr viral load test come back negative. 21 days after I took hiv 1 & 2 ab/ag duo came back negative. Then 26 day after I took another hiv 1& 2 ab/ ag duo test which came back negative. Doctor tell me my test are conclusive.

    • Dr. Julian Ng

      Hi,

      The recommendation is to do the 4th Generation HIV test 28 days after exposure in order for results to be considered conclusive.

      • Akshay kumar

        Dear doctor I have hiv 1&2 combo after 35 days negative my result conclusive

  12. Hi dr tan..

    Iam circumcised male,

    What is the chance of hiv transmission single unprotected vaginal sex exposer…
    Hiv positive female partner…

    What the hiv windowperiod…

    Some doctors say hiv windowperiod up to 10 year’s take hiv test every 3 months.,

    2 years post exposure hiv test all negative….

    • Dr. Julian Ng

      Hi,

      I would consider your test as conclusive. Please move on with your life.

  13. hi doctor do i need to do a retest after 25days and 5weeks negative 4th gen cmia test?

    • Dr. Julian Ng

      Hi,

      If oyu have been tested with a 4th generation HIV test after 5 weeks, it is conclusive. If you are still concerned, you may wish to repeat after 3 months.

  14. Worried sick

    Hi doctor, suffered a recent accidental needle stick. Shortly there after I developed pretty much every ars symptom on the list. I took a test at 2-4-6-and 10 weeks 4th generation ag/ab. Also I had sex with my wife 3 days after the possibke exposure. My questions are how accurate are my result?if I am hiv positive, what are the chances I could have infected my wife 3 days post exposure?

  15. Hello doctor thank you for always answering our questions
    My questions are about the accuracy of the RNA Qualitative TMA assay HIV early detection at 9 weeks of post exposure and the 4th Generation with reflexes at 6 weeks and 12 weeks it’s there any change of giving a false negative results? Do you know about anyone getting a false negative result on any of these tests? After all these tests can I still be positive on HIV without sowing it on the tests that I have done? Thank you

  16. Hi Doctor,
    I was put on PEP 5 hours after a very high risk sexual exposure which i completed for the 28 days. 4 days after completing PEP I took a P24 and Antibody 4th generation test which came back negative. At 17 days post-pep I took another negative 4th generation antibody test. I know I need to test at 1 month post-pep, but do you think my results could change from a negative to positive without any further risky exposures/

    • Dr. Julian Ng

      Hi,

      The result from tests thus far are reassuring but to be conclusive you will need to be retested. There is no way to ascertain whether a negative result can become positive if the tests are performed before the recommended time frame.

  17. hi doc.does a negative 4th gen cmia test after 35days need to retest after 3month? have you seen a negative 4th gen test after 1month turned positive? and whats the earliest detection you had in your lab?

    • I would consider your tests conclusive already. The earliest detection I have had is 14 days post-exposure with a 4th gen combo test.

  18. Hiv 1/2 and p24 CMIA serum combo test negative after 46th day is this enough for test or should I retest more

    • Dr. Julian Ng

      Hi,

      The result is conclusive. However if you are still concerned, you can consider repeating 3 months post-exposure.

  19. I have protected pay sex with a girl .Then after 14days rna par test was negative.
    After 21 days p24 combo ab|ag test negative
    Plz tell me my test are conclusive

    • I would say your tests are an extremely good indication, but for conclusive results we would recommend a 4th gen combo test at 28 days or more.

      • Sir I took pep medicine for 3 day {only 3 pills} after 54 hours. Can it affect my result

      • Akshay kumar

        Now after 26 days I test again hiv 1&2 combo it is negative. My result conclusive

  20. hi dr. i got tested for 4th generation cmia after 25th day and 5 weeks both are negative is this conclusive? should i need to retest after 3mos? my exposure was protected vaginal sex.thanks

  21. Hi Doctor ,

    I am from India, Age 33 ,Male. Due to unavoidable circumstances had unprotected oral sex (Received 60 sec) with unknown status lady in spa.From that day i lost the Sleep. I am running life with fear
    I had test
    1) HIV 24 Antigen Assay at 14 th day – Negative
    2) HIV combi ( Ag/ Ab ) test at 25 th day – Negative
    3) HIV I & II at 36 th day – Negative.
    4) HIV P24 – Ab ECLIA at 37 th day – Negative
    5) HIV I – Ii at 42 day – Negative

    In 15 th day I had sore throat. And 20 th Day Urinary Tract Infection , after Levofloaxin antibiotics it reduce 90 % but still exist little bit .
    In 5 th week Heptatis B and Sysphilis are negative.Urine test for Gonorea also negative.

    Foot and finger has inflammation and yesterday i start to feel little muscle pain and mild testicle pain .In full body checkup ESR 70mm/HR, lymbocutes 51% and Polymorph has 40% .Other value are ok doctor said.

    Is it HIV test are conclusove ?

    • Dr. Julian Ng

      Hi,

      HIV transmission via oral sex is very low. Your results thus far is reassuring. Please visit a docotor for further evaluation of your symptoms as they may be due to other medical issues.

      • Okay Doctor.I had consult with doctor and prescribed same tablet for another week.Now feel okay. Other symptom are gone now.
        Now My fear is only about HIV. As per results , Shall I relax ? Or Need to wait or another month .

      • From your reply i am getting more fear, ” Thus Far ” means , is it any possible result will change ?

        • Dr. Julian Ng

          Hi,

          As in my previous reply, your tests results are conclusive. However you still need to see a doctor especially if your symptoms do not resolved as they could be due to other medical conditions.

          • Thanks Doctor . yes I am already consulting with doctor. I am taking prescription. Society need more awareness regarding oral sex HIV AND STD and Need more public advertisement for oral sex and STD .
            Once again Thanks for you and your organisation for great service.

  22. Dr would like to know how is the risk and my test accurate or not?
    1. Protected sex with condom?
    2. Pcr rna test at 10days after exposure? Undetected
    3. 4th gen test ag/ab at 27days after exposure together with the girl tht i had protected sex. (All test negative)

  23. badthink

    Hi sir..
    Which company hiv 4th generation test used your clinic…
    16 months post exposure hiv alere combo p24 antigen test negative…
    It is conclusive….
    Iam 100% negative…
    In future said become positive any further test needed…

    My question:
    This year june iam get married make childrens happy life i cannot sleep eat ….
    Pls answer my question…

  24. badthink

    Hi dr than

    Which company hiv 4th generation test used your clinic…

    16 months post exposure hiv alere combo p24 antigen test negative…
    It is conclusive….
    Iam 100% negative…
    In future said become positive any further test needed…

    This is my last question….
    Pls say clear answer….

    Thank you again and again….

  25. Dr. I just conduct a pcr rna test at the 10days (13 march to 23 march) after protected sex vaginal with my gf. The result was undetected. And on 26days combo test. Is the test conclusive?

  26. badthink

    Hi dr..tan

    Hiv lay dormant many years can’t detect hiv any test..it is true….

    Which company hiv 4th generation test used your clinic…

    16 months post exposure hiv 4th generation alere combo negative..
    It is 100% negative…

    This year june iam get married make childrens happy family iam still worried..

    Pls help. Me

    • No, it is not true that HIV can stay undetectable for many years. I would consider your test conclusive. Please move on with your life.

  27. WorriedGuy

    Hi Doctors,

    I hope you can give me an expert advise. I was taking oral Isotretinoin 20mg everyday for 7 months already when I had my HIV test. I’ve read that Isotretinoin can be used for chemotherapy (which they say extends the window period to 6 months since chemo makes you immunosupressed).

    I already tested Non-Reactive using ELISA 4th Gen Ag/Ab Combo at 7 weeks after exposure.

    1. Does taking Isotretinoin really extends the window period?
    2. Do you think it could have affected my 7 weeks result?
    3. Do you think my 7 weeks result is already conclusive or is there a chance that it will still change at 3 months or 6 months?

    Hope that you can help me with my concerns. I am just really worried right now. Thank you in advance.

    • Dr. Julian Ng

      Hi,

      Isoretinoin does not affect the HIV results you took. Generally, 4th Generation HIV tests are conclusive after 28 days post-exposure. However, if you are still concerned, you can consider repeating it after 3 months.

      • WorriedGuy

        Additional concerns Doc.

        1. But in your opinion and experience with your patients, do you think my 7 weeks result can still change?
        2. Is 4th Gen only conclusive when you take it at exactly 28 days? And when you test beyond that, would the window period be extended until 3 month already? Like in my case I had the test at 52 days.

        Thanks in advance.

        • Dr. Julian Ng

          Hi,

          As long as the HIV 4th Generation test is done after 28 days, it is generally reliable. If you are still concerned, please consider repeating HIV test 3 months post-exposure.

  28. cool001

    Hi dr tan…
    Replay me pls…
    It is possible…
    1year post exposure westrenblot negative.
    16 months post exposure hiv rna qualitative result not detected.

    1)I have read on this site that is possible to not have antibodies (test negative) during end stage AIDS.

    Pls telme no sleep..properly..
    Iam 100 % negative.
    Any test needed.
    This year june iam get married make happy children’s and family.pls answer this question

  29. cool001

    Hi dr.tan

    Iam single unprotected vaginal sex with a girl.later 9 months found she is hiv positive.

    16 months post exposure hiv rna pcr qualitative not detected.
    4th generation alere combo negative.
    Westren blot negative.
    Iam negative..
    Any further test needed….

    1.Some doctor say hiv lay dormant 10years it is true.(focus this point)

    2.iam get married this year june and make childrens happy family.
    Iam 100 % negative or not. (Focus this point)

    3.4th generation hiv alere combo 28 days ofter 99.9 accuracy.
    16 months post exposure 4thgeneration alere combo negative iam 100% negative.
    Any further test needed.(focus this point)

    4.which 4th generation hiv kit company used your clinic.

    Pls say clear answer 1,2,3,4 question.

  30. Hi doctor
    I had unprotected vaginal sex with a female of unknown status
    At 3 weeks post exposure i had a mild sore throat which was followed by a rash on my back.i did a 4th generation alere test at 34days and the results came back negative.my concern is that i still have a rash on my back,thighs and face And swollen lymph node on my right arm(not sure)
    1.Were my results at day 34 post exposure conclusive?
    2.is my rash related to hiv?
    3.is there a posibility of the results turning to positive at 12weeks?

    • Dr. Julian Ng

      HI,

      I would consider your 4th generation HIV test as conclusive at 34 days. The rash is not related to HIV. Please see a doctor for your ongoing symptoms.

      • Thank for your answer doctor..is there a possibility of the results turning positive at 12weeks given there is no other past event?

        • Dr. Julian Ng

          Hi,

          Generally, the 4th Generation HIV test is reliable after 28 days post-exposure. However if you are still concern, the advise would be to repeat it 3 months post-exposure.

          • Thank for your answer doctor
            But one more last question.. Have seen results that were negative at 28 days turning positive at 3months?

  31. cool001

    Here is my question and thank you so much in advance.

    (1) I had a possible exposure 16 months ago(unprotected vaginal sex, 9 months later found she is hiv positive ).

    (2) 9 months after , I had a westren blot test and it was negative.
    16 months post exposure hiv rna pcr qualitative result not detected.

    (3) I have not had any sexual activity with anyone for the last 16 months since that possible exposure.

    Since I am going to be married soon , I wanted to put any worries beyond doubt, so still today I tested using alere combo result negative .

    First question:

    Even though it might sound silly, Could anyone with expertise tell me if I could definitely say that I am 100% free of infection?

    Second question:

    (2)The person I talked to when get my recent test result said no test is 100% accurate. I wonder if , after 16 months post exposure (without any other sexual activity in between), those test results are not absolutely conclusive in my case?

    One doctor told me hiv lay dormant up to 10 years it is true.
    iam 100% negative….

    • Dr. Julian Ng

      Hi,

      In life, there is nothing 100% most of the time. However based on your results thus far, I would consider them conclusive and you should move on with your life.

  32. cool001

    Hi sir…..

    One doctor told me hiv lay dormant many years up to 10 years it is true…..

    What is the exact hiv windowperiod…..

  33. Hi Doctor I had a possible exposure (high risk group) on the 22nd February and was put on PEP 3h after the exposure. I completed the full course. One week after finishing PEP (5 weeks post exposure) I had a HIV Duo 4th Generation which came back negative for antigen and antibodies. I know this is not ‘conclusive’, but do you think it fair to say my chances of testing HIV positive due to this incident are EXTREMELY small now?
    Thank you

    • Dr. Julian Ng

      Hi,

      I would consider your HIV result as reassuring. If you are still concerned, you should visit a doctor for further evaluation.

  34. Hello Dr i have been dating a girl and almost every time i do its sex to her a few days later I get sore throat and flu like feeling that usually go away could is there a possibility that she has some infection? Also how long do I wait to take an std and hiv test? Thanks

    • Hello Dr i have been dating a girl and almost every time i do oral sex to her a few days later I get sore throat and flu like feeling that usually go away could is there a possibility that she has some infection and she passed on to me?Also how long do I wait to take an std and hiv test? Thanks

      • Dr. Julian Ng

        Hi,

        Risk of HIV transmission via oral sex is generally very low. However other STDs such as gonorrhoea and chlamydia can be transmitted via oral sex. If you are concerned, please visit your doctor for further assessment. if you prefer, you can visit us at: http://www.drtanandpartners.com/where-to-find-us/

  35. Pls doctor reply me is 60 days 4th generation tridot test is conclusive

  36. But i did the 4th generation tridot test at 60 days it came back negative so i need anthoer test at 12 week?

  37. I had sex with sex worker on jan 04 2018 condom was broked but not ejacute inside her after one week hiv 1&2 test was negative and after 26 days 4th generation hiv1&2 hbsag hcv are came back negative and 8 week of tridot test is also came back negative but still i feel some ARS symptoms after 10 week so i decided to take another test on 12 week post exposure so please help that is my test are conclusive and the 12 week test is turn postive ? So please guide me doctor

  38. I had sex with sex worker on jan 04 2018 condom was broked but not ejacute inside her after onw week hiv 1&2 test was negative and after 1 month 4th generation hiv1&2 hbsag hcv qre came back negative and 8 week of tridot test is also came back negative but still i feel some ARS symptoms after 10 week so i decided to take another test on 12 week post exposure so please help that is my test are conclusive and the 12 week test is turn postive ? So please guide me doctor

    • Dr. Julian Ng

      HI,
      Given that you did the 4th Generation HIV test 1 month post-exposure, I would consider your results as conclusive. Your symptoms is very likely not due to HIV. Please seek further evaluation of your symptoms with a doctor.

      • Sry not at one month exactly at 26 daysof post exposure pls tell me that is conclusive or not

        • Dr. Julian Ng

          Hi,

          My suggestion is to retest after 28 days post-exposure.

          • But i did tridot test of 4th generation at 8 week exactly at 60 days doctor say is conclusive whether it is conclusive or not?

  39. Hi sir ….
    Morning, firstly this forum is proving to be a big help at this time to me. Just a question to throw out there to everybody. have read on here that transmission of HIV is very difficult from female to male vaginal sex -iit is true.
    1)Iam unprotected vaginal sex single exposer hiv positive girl.iam circumcised male.male circumcised reduce the risk it is true.
    2)15 months post exposer my hiv westren blot ,hiv rna pcr qualitative ,4th generation test ,elisa,tridot all are negative.
    3)what is the exact hiv windowperiod.
    5)some doctors says every 6 months take hiv test hiv windowperiod is 3 months to 10 years it is true.
    6) iam take every 6 months hiv test ar any further test is nedded.
    7)iam worried this reason about my partner hiv positive but my test result all are negative any delay seroconversion iam become positive.
    8)iam thinking all.ways my partner hiv positive but still iam negative but future said it is come positive.no sleeep..,no eat……only think hiv………… pls clarify me
    thank you for your great job…..
    Delay seroconversion My result is change in future….

  40. Hi Dr. Tan

    I’ve had a protected sex encounter 9 weeks ago. I had a cold sore which was about to break but never gave the girl oral but only kissed. I did receive oral though.

    Last week which was week 8 after the encounter I started having a fever which led me to doing the 4th Gen p24 hiv ag/ab test. The results came back negative.

    Would you consider this as conclusive?

    One of my doc said yes and another doc of mine and government authorities suggested another test during the 12th week or 90th day mark.

    I’m jus lost and I really want to put this matter out of my life.

  41. Hello Dear Medical Team,

    how conclusive are negative results of BOTH HIV PCR as well as 4th generation Combo Test taken together on day 16 after potential exposure? In the PCR section you mentioned 100% conclusiveness after 10 days but opinions seem to vary on that.

    Worries arose due to a cold with a slight fever at day 23.

    Many thanks in advance for your help.

    • Dr. Julian Ng

      Hi,

      Generally, the recommendation is that a repeat 4th Generation Combo test is required if the testing was done within the 28 day window period. CDC do not recommend the use of HIV PCR for screeening for HIV infection.

  42. Hello doctor,
    I have done RNA PCR on day 15 it came out undetectable and i have also done the 4th Generation test on day 29th and it it came out negative. How conclusive is my result?

    I am a little worried because i have this daily night mild sweat which happen around my chest and i have also been experiencing abdominal pain which happened randomly since my last activity with an unknown CSW status.

    Kindly need your advice on this matter doctor.

    • Dr. Julian Ng

      Hi,

      Generally, if testing of HIV is done 28 days after exposure using a 4th generation HIV test, then the result is conclusive. Please visit a doctor to evaluate your symptoms further as they may not be related to HIV.

      • thanks doctor for your prompt response.I will go and see a doctor as your advice.

  43. prathap

    Hi sir ….

    Morning, firstly this forum is proving to be a big help at this time to me. Just a question to throw out there to everybody. have read on here that transmission of HIV is very difficult from female to male vaginal sex -iit is true.

    1)Iam unprotected vaginal sex single exposer hiv positive girl.iam circumcised male.male circumcised reduce the risk it is true.
    2)15 months post exposer my hiv westren blot ,hiv rna pcr qualitative ,4th generation test ,elisa,tridot all are negative.
    3)what is the exact hiv windowperiod.
    5)some doctors says every 6 months take hiv test hiv windowperiod is 3 months to 10 years it is true.
    6) iam take every 6 months hiv test ar any further test is nedded.
    7)iam worried this reason about my partner hiv positive but my test result all are negative any delay seroconversion iam become positive.
    8)iam thinking all.ways my partner hiv positive but still iam negative but future said it is come positive.no sleeep..,no eat……only think hiv………… pls clarify me
    thank you for your great job…..

    Delay seroconversion My result is change in future….

  44. Hello doctor!

    I had unprotected vaginal sex for less than 20 seconds, afterwards I’ve put on condom to finish off the sex on Jan.

    30 days (4 weeks) after the intercourse, I did 3rd Gen – Test was NEGATIVE.

    50 days (7 weeks) after the intercourse, I did 4th Gen duo – Test was NEGATIVE.

    Do you consider my test as conclusive? I was told that it is 99.99% accurate for the 4th Gen test on the 50th day….

    • Dr. Julian Ng

      Hi,

      Generally, your test result with the 4th Generation HIV test on day 50 post-exposure is conclusive.

  45. Hi doc,
    I had a broken condom exposure. I took a few hiv tests.

    Day 23.5 4th gen alere combo by AFA negative

    Day 29 4th gen SD Bioline combo by your clinic negative

    Day 55 4th gen alere combo by DSC negative

    Just curious do i still need testing? I suspect i have an std as im showing symptoms. At day 55 i went for std blood test as well as HIV (neg). I am having my blood test results in 2 weeks for stds. Could i hve also caught HIV?

    • Dr. Julian Ng

      Hi,

      With repeated testing with 4th Generation HIV tests even at day 55 post-exposure, I would say that your results are conclusive.

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